Tuesday, September 20, 2011

7.Peyronie's Disease: A Rare Or Common?

Peyronie's Disease: A Rare Or Common?
Peyronie's disease: a rare or common?

Peyronie's disease (PD) is considered a rare disease of the connective tissue of the penis, which has no known cause or cure, although the mechanism of how PD starts celluar is not completely understood. Three main diagnostic criteria of the RFP are required to establish a diagnosis of Peyronie's disease, although there is no universal agreement even on the following: 1) the existence of a node or an band of varying sizes made of fibrous tissue) is called a chielfy scar or membrane plate in a thin but tough tissue known as the tunica albuginea, 2) variable pain that occurs during construction, and 3) the curvature or bending of the penis, which was not present before the start of PD. Most men with PD retain the ability to develop and maintain an erection. Because of the physical and functional changes in DCs, these men have problems with vaginal penetration caused by abnormal curvature, impotence, or pain for both partners during insertion.

Since only those people who personally deal with PD do not know anything abot, most lay people assume is a rare condition. This is not the case at all.

Recent review of the prevalence of Peyronie's Disease

As some reports indicate that, Peyronie's disease occurs in adult males only 200 (0.50%) in the United States, this figure can be extrapolated to show that 1.4 million people have Parkinson's. Despite this, Peyronie's disease presents as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institute of Health (NIH), because the statistics of others, have developed suggests PD affects less than 200,000 U.S. men.

Several studies of Peyronie's disease in late 1980 reported that the prevalence of 0.4% to 2.0% of adult U.S. men.

Since there is a tendency for men to exaggerate both, in some cases on issues related to sexuality, but at the same time to be shy and withdrawn in certain matters of sexuality, data on the incidence of PD was more variable and unreliable. Prior information on the frequency of PE is based on surveys and interviews with self-reported and verified, so the actual rate of occurrence was merely an approximation or best guess.

A recent study of this question used stduy large groups of men with known or suspected of PD, and cross-sample accuracy of the information collected:

· Schwarzer and colleagues created the PD questionnaire and sent it to him in 8000 in Cologne, Germany. The response rate for men was a survey of more than 55%, rather high. The results showed the presence of Peyronie's disease is a normal male population (average age 57.4 years) was higher than expected by 3.2%. Among men aged 30-39 years, 1.5% showed a hardening of local tissue, suggestive of PD, men 40-49 years of age increased from 3.0% in men aged 50-59 years and the rate incrased 4.0% interest. That the presence of tissue density, or hardening increases with age by 6.5% in men older than 70 years.

· Matkov and his researchers found that 30 (7%) of Peyronie's disease were studied 453 were aged under 40. Important features of this younger group PD included: (1) recalled a traumatic event specifications during sexual intercourse, where the "ram" or "blocking" was held, which was considered the beginning of the problem PD ( 2) moderate to high pain during erection with a major complaint, (

• The Department of Urology, Loyola University Medical Center, Maywood, Illinois, conducted a study to determine the prevalence of Peyronie's disease in a group of men to detect prostate cancer in the United States. In this study, 534 men of Loyola has provided a medical history, received a physical examination by a urologist and completed a Sexual Health Inventory for Men (SHIM) questionnaire. A diagnosis of Peyronie's disease is formed, if the presence of a palpable lump in the penis could be done. As a result, 48 men in this study were found to have a palpable nodule on physical examination to detect the occurrence of Peyronie diseae 8.9%. The average age of men with Peyronie's disease was 68.2 years, compared with an average age of 61.8 years for men without Peyronie's disease. This study concluded that the prevalence of Peyronie's disease is hihg in the general population, especially in elderly populations, as previously reported in the series.

Conclusion

These and many other recent studies and reviews of medical literature shows a lot of Peyronie's disease usually is more common in men than previously thought, and increasingly common in the elderly population. Average of PD onset is about 53 years. Although it is still little known in the general population, it is not really even a well-known within the medical community. This disease is "rare" is apparently broader and less rare than the previous measures reported.

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